COVID-19 Convalescent Plasma Program – Donors

We are so grateful that you want to help patients in need. You must work closely with the healthcare provider or public health department who made your diagnosis (or that provider’s office staff), because there are several pieces of documentation you must have in order to donate.

If you have ever been a blood donor, the process will be very similar, except it will take a bit longer than a standard blood donation. This procedure is called “apheresis plasma donation,” and we can provide you with more details when we talk to you to schedule your donation.

COVID-19 Convalescent Plasma donations can ONLY come from donors who have fully recovered from a confirmed COVID-19 infection AND have successfully completed an eligibility process in cooperation with their physician and LifeStream Blood Bank’s Medical Services team. If you believe you are eligible to donate COVID-19 Convalescent Plasma, please click below or call 909-386-6837.

Ask yourself these questions:
  • Did I have a proven COVID-19 infection? In other words, did my provider or hospital perform a laboratory test that confirmed that I had COVID-19? (this is usually a swab test inserted into your nose and possibly throat as well)
    • You will need a copy of the lab report or a written statement from your physician giving the test type, the result, and the date it was taken in order to donate
  • If I did NOT have a test when I got sick, did I have an antibody test after I recovered proving that I had COVID-19?
    • You will need a copy of the lab report or a written statement from your physician giving the test type, the result, and the date it was taken in order to donate
  • When was the exact last day I had symptoms of COVID-19?
    • You must have been completely without symptoms for at least 14 days (that includes taking no anti-fever medications, cough medicines, or other cold/flu medicines)
  • After I recovered, did I have a NEGATIVE COVID-19 test? 
    • If “YES,” you can donate when you’ve been symptom-free for at least 14 days
      • You will need a copy of the lab report or a written statement from your physician giving the test type, the result, and the date it was taken in order to donate
    • If “NO,” you will have to wait until you’ve been completely symptom-free for at least 28 days before you can donate
  • Did I have a test that shows I have made antibodies against COVID-19?
    • This is not required, but please supply antibody test results if you had the test done.

If you are a female who has ever been pregnant, we may ask you to come in a few days early in order to collect a blood sample before your actual donation. This is because pregnancy and childbirth can lead to formation of specific antibodies that would make you unable to donate a plasma product (these antibodies are not related to COVID-19 infection).

  • ​LifeStream does not test donors or blood products for ACTIVE COVID-19 infection. 
  • LifeStream Blood Bank is now testing all successful blood donations for COVID-19 antibodies. Your antibody testing results reveal your potential to donate convalescent plasma, a powerful way to help those fighting COVID-19. The antibody test will indicate if the donor’s immune system has produced antibodies because of previous exposure to the virus. This is not a test that tells a person whether or not they have a current COVID-19 infection. If you are feeling unwell, please do not donate blood. For more info about antibody testing, click here.
  • LifeStream does NOT provide directed donations to specific facilities or patients. When a donor donates convalescent plasma on behalf of a hospital, we reserve some of the products from that collection for that hospital’s use. The hospital then decides how to distribute the product in their facility, based on their own criteria. We work with donors and hospitals to make this happen every day through this web page, and we are appealing to recovered COVID-19 patients throughout our area to contact us to arrange a convalescent plasma donation.

If you have been told that you are permanently ineligible to donate blood as a volunteer, you will not be able to donate convalescent plasma at this time.

If you have read this far and you believe you will qualify, please click below to fill out the online form.

For further questions, please email covidplasma@LStream.org, or call (909) 386-6837.
Frequently Asked Questions

LifeStream’s Response to New York Times and CNN Reports on COVID-19 Convalescent Plasma (CCP)

Q: I’ve heard about some recent news reports on FDA’s opinion on COVID-19 Convalescent Plasma (CCP). What did those reports say?

A: On August 19, both the New York Times and CNN reported that the FDA had decided to “hold” their pending “emergency use authorization” of the use of CCP.  The headlines contained phrases like, “Government health leaders including Dr. Francis S. Collins and Dr. Anthony S. Fauci urged caution last week, citing weak data from the country’s largest plasma study.” At first glance, this information appears to be “bad news” for CCP, but the reality is different.

Q: What would “emergency use authorization” of CCP mean?

A: An FDA emergency use authorization (or “EAP”) simply would mean that physicians could order and transfuse CCP without needing to enroll their patient in a research study. Currently, all CCP transfusions must occur under the umbrella of research. The vast majority of hospitals are using the “Expanded Access Protocol” (EAP) sponsored by the Mayo Clinic.

Q: Does this mean that FDA has “given up” on the hope that CCP will be an effective product for treating COVID-19 patients?

A: It is very important not to overreact to this decision. FDA has not made any statements suggesting that CCP is not an effective product. Functionally, this decision just means that FDA wants CCP transfusions to continue under research conditions for now, until more data is available from those studies. In fact, there are already several preliminary studies suggesting a positive effect from CCP transfusion to COVID-19 patients.

Q: Should recovered COVID-19 patients still be encouraged to donate CCP?

A: A resounding “YES!” LifeStream receives requests for CCP from hospitals all across Southern California every day of the week. The need has not gone away, and we anticipate that the early results mentioned above showing positive results will increase demand in the coming weeks and months. To inquire about donating CCP, recovered COVID-19 patients should click on the button above or call 909-486-6837.

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