COVID-19 Convalescent Plasma Program – Donors

We are so grateful that you want to help patients in need. You must work closely with the healthcare provider or public health department who made your diagnosis (or that provider’s office staff), because there are several pieces of documentation you must have in order to donate.

If you have ever been a blood donor, the process will be very similar, except it will take a bit longer than a standard blood donation. This procedure is called “apheresis plasma donation,” and we can provide you with more details when we talk to you to schedule your donation.

Attention: Individuals with history of pregnancy
LifeStream is no longer enrolling individuals with a history of pregnancy into the CCP program. The program ends on April 30, which would not allow enough time to determine CCP donation eligibility for individuals with a history of pregnancy – a process that can take a few weeks with pre-testing before donation.  However, the need for whole blood and platelet donations has not changed. Those donations are needed every day, and we urge you to please make an appointment to donate whole blood or platelets.

COVID-19 Convalescent Plasma donations can ONLY come from donors who have fully recovered from a confirmed COVID-19 infection AND have successfully completed an eligibility process with LifeStream’s Medical Services team. If you believe you are eligible to donate COVID-19 Convalescent Plasma, please fill out the Donor Questionnaire below.

Ask yourself these questions:

  • Did I have a proven COVID-19 infection? In other words, did my provider or hospital perform a laboratory test that confirmed that I had COVID-19? (this must be a swab test inserted into your nose and possibly throat as well)
    • You will need a copy of the lab report or a written statement from your physician giving the test type, the result, and the date it was taken in order to donate
  • If I did NOT have a test when I got sick, can I still donate COVID-19 Convalescent Plasma?
    • No.  You must have had a diagnostic test confirming your results.
  • When was the exact last day I had symptoms of COVID-19?
    • You must have been completely without symptoms for at least 14 days (that includes taking no anti-fever medications, cough medicines, or other cold/flu medicines)
  • After I recovered, did I have a NEGATIVE COVID-19 test? 
    • If “YES,” you can donate when you’ve been symptom-free for at least 14 days
      • You will need a copy of the lab report or a written statement from your physician giving the test type, the result, and the date it was taken in order to donate
    • If “NO,” you will have to wait until you’ve been completely symptom-free for at least 28 days before you can donate

If you are a female who has ever been pregnant, we may ask you to come in a few days early in order to collect a blood sample before your actual donation. This is because pregnancy and childbirth can lead to formation of specific antibodies that would make you unable to donate a plasma product (these antibodies are not related to COVID-19 infection).

  • ​LifeStream does not test donors or blood products for ACTIVE COVID-19 infection. 
  • LifeStream Blood Bank is now testing successful whole blood donations for COVID-19 antibodies. Your antibody testing results reveal your potential to donate convalescent plasma, a powerful way to help those fighting COVID-19. The antibody test will indicate if the donor’s immune system has produced antibodies because of previous exposure to the virus. This is not a test that tells a person whether or not they have a current COVID-19 infection. If you are feeling unwell, please do not donate blood. For more info about antibody testing, click here.
  • Please DO NOT refer family members to LifeStream to donate plasma exclusively for their loved ones. LifeStream does NOT provide COVID-19 Convalescent Plasma directed donations to specific facilities or patients. The process of “directed donation” (collecting plasma from a specific donor for use by a specific patient), is much more difficult and time-consuming than collection from the overall group of recovered COVID-19 patients. Given the massive recent increase in demand for CCP in our region and across the US, we are working urgently to increase the overall supply of this product for ALL patients.

If you have been told that you are permanently ineligible to donate blood as a volunteer, you will not be able to donate convalescent plasma at this time.

If you have read this far and you believe you will qualify, please click below to fill out the online form.

For further questions, please email, or call (909) 386-6837.
Frequently Asked Questions

LifeStream’s Response to New York Times and CNN Reports on COVID-19 Convalescent Plasma (CCP)

Q: I’ve heard about some recent news reports on FDA’s opinion on COVID-19 Convalescent Plasma (CCP). What did those reports say?

A: On August 19, both the New York Times and CNN reported that the FDA had decided to “hold” their pending “emergency use authorization” of the use of CCP.  The headlines contained phrases like, “Government health leaders including Dr. Francis S. Collins and Dr. Anthony S. Fauci urged caution last week, citing weak data from the country’s largest plasma study.” At first glance, this information appears to be “bad news” for CCP, but the reality is different.

Q: What would “emergency use authorization” of CCP mean?

A: An FDA emergency use authorization (or “EAP”) simply would mean that physicians could order and transfuse CCP without needing to enroll their patient in a research study. Currently, all CCP transfusions must occur under the umbrella of research. The vast majority of hospitals are using the “Expanded Access Protocol” (EAP) sponsored by the Mayo Clinic.

Q: Does this mean that FDA has “given up” on the hope that CCP will be an effective product for treating COVID-19 patients?

A: It is very important not to overreact to this decision. FDA has not made any statements suggesting that CCP is not an effective product. Functionally, this decision just means that FDA wants CCP transfusions to continue under research conditions for now, until more data is available from those studies. In fact, there are already several preliminary studies suggesting a positive effect from CCP transfusion to COVID-19 patients.

Q: Should recovered COVID-19 patients still be encouraged to donate CCP?

A: A resounding “YES!” LifeStream receives requests for CCP from hospitals all across Southern California every day of the week. The need has not gone away, and we anticipate that the early results mentioned above showing positive results will increase demand in the coming weeks and months. To inquire about donating CCP, recovered COVID-19 patients should click on the button above.

Translate »